newborn screening programme

Congenital adrenal hyperplasia

We are no longer accepting comments on this condition.
Register for updates and we will notify you when we have reviewed all comments along with the scientific evidence.

Congenital Adrenal Hyperplasia (CAH) is the name given to a group of disorders. These cause impaired production of a chemical called cortisol.

UK NSC screening recommendation Based on the last UK NSC review of this condition that occurred in December 2016.

Screening is not currently recommended for this condition.

Screening CAH is not recommended because:

  • there is still some uncertainty about how common CAH is, particularly in some groups of the population
  • there is not enough information to determine which groups of people should be included in any future screening programme
  • currents tests are not accurate enough and may miss babies or give false positives
  • studies show that screening may not be effective at reducing deaths from CAH
  • screening may take place too late to benefit people with some types of CAH

Supporting documents from the 2016 review

Evidence summary Congenital adrenal hyperplasia (2016)
This document provides the evidence on which the current UK NSC recommendation is based.

UK NSC coversheet & consultation responses (2016)
This document summarises the review process including the public consultation comments.

Review cycle

Date previous review completed: 2016

Next review estimated to be completed: 2021 to 2022.

To see previous evidence reviews, visit the UK NSC archive.

Organisations interested in Congenital adrenal hyperplasia

These organisations have expressed interest in this recommendation and may submit responses to evidence reviews.

List of organisations

If you think your organisation should be added, please contact us. More information for organisation can be found in appendix C of the UK NSC evidence review process.