newborn screening programme


A baby with Glutaric Aciduria Type 1 (GA1) has problems breaking down certain amino acids. Children with GA1 become very ill from minor illnesses, like tummy aces or chest infections. They must have immediate hospital treatment if this happens. Without treatment the disease can result in coma, brain damage, and death.

Read more about GA1 on the NHS website.

UK NSC screening recommendation Based on the last UK NSC review of this condition that occurred in May 2014.

Screening for this condition is recommended.

The UK NSC has recommended screening for GA1 within the current Newborn Blood Spot Screening Programme. A one year evaluation of screening in the UK found that screening for this rare inherited organic acid disorder will identify babies early and lead to treatment to help prevent serious problems developing.

Supporting documents from the 2014 review

Screening around the UK

The UK NSC recommends screening for this condition, however this may vary slightly depending on where you are in the UK.

Review cycle

Date previous review completed: 2014

Next review estimated to be completed: 2021 to 2022.

To see previous evidence reviews, visit the UK NSC archive.

Organisations interested in GA1

These organisations have expressed interest in this recommendation and may submit responses to evidence reviews.

List of organisations

If you think your organisation should be added, please contact us.